Yes, the loose spoke nipple protrudes into the protective tube
tape and could wear a hole in the tape as well as the tube itself.
The problem could be woursened if the nipple is very loose and the
tube or tire pressure is over inflated.
The fix would be prevention of the nipple loosening.
Another problem could be when a nipple is too tight and the
spoke protrudes out of the end of the nipple and wears a hole in
the tube tape and tube.
You might get lucky by doing this: deflate the tire, tighten the
spoke nipple then inflate the tire to proper psi, then spit on your
finger and place the saliva onto the tube and schrader valve: wait
and see if bubbles are produced if so tighten the schrader valve
and you are set to go.